GLS Pharma Ltd

Leuprolide acetate is a gonadotropin-releasing hormone (GnRH) agonist. Leuprolide acetate is approved for palliative treatment of advanced Prostate cancer.

Leuprolide acetate is a gonadotropin-releasing hormone (GnRH) agonist. Leuprolide acetate is approved for palliative treatment of advanced Prostate cancer.

Leuprorelin acts as an agonist at pituitary GnRH receptors. By interrupting the normal pulsatile stimulation of, and thus desensitizing, the GnRH receptors, it indirectly downregulates the secretion of gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to hypogonadism and thus a dramatic reduction in estradiol and testosterone levels in both sexes

Indications:

• prostate cancer
• It may also be used for estrogen-dependent conditions such as endometriosis or uterine fibroids.